Multiple antibiotic-resistance mechanisms including a novel combination of extended-spectrum β-lactamases in a Klebsiella pneumoniae clinical strain isolated in Argentina
نویسندگان
چکیده
1474, p. 165. American Society for Microbiology, Washington,
منابع مشابه
Detection of CTX-M-β Lactamases form Isolated Klebsiella pneumoniae
Background and Objective: Organisms producing CTX-M β-lactamases are emerging as a source of resistance to oxyiminocefalosporins such as ceftriaxone and ceftazidime. However, the laboratory detection of these strains is not well defined. In this study, phenotypic assay for screening of extended-spectrum β-lactamases producing strains and molecular assay for the identification of CTX-M β-lact...
متن کاملتشخیص متالوبتالاکتامازها، بتالاکتامازهای با طیف وسیع و پورینهای غشاء خارجی در ایزولههای کلبسیلا پنومونیه جدا شده از بیماران بستری در بیمارستانهای شهر تهران
Background and Objective: Klebsiella pneumoniae is one of the most important causative agents both in form of hospital acquired and community-acquired infections. This bacterium is one of the most prevalent pathogens that is isolated from hospitals and is associated with high mortality rates. The uprising trend of multi drug resistance among Klebsiella pneumoniae has limited the treatment optio...
متن کاملPrevalence of Extended-spectrum Beta-lactamases (ESBL) Types blaTEM and blaSHV in Klebsiella pneumoniae Strains Isolated from Clinical Samples by PCR in Miandoab, West Azerbaijan
Background and Objective: Beta-lactamases are the most important factors in the resistance to beta-lactam antibiotics among gram-negative bacteria, especially Klebsiella pneumoniae. Nowadays, the prevalence of infections caused by extended-spectrum β-lactamases (ESBLs)-producing K. pneumoniae is increasing, as one of the emerging health problems throughout the world. This study aimed to investi...
متن کاملAntibiotic Resistance Pattern and the Prevalence of Extended Spectrum Beta-Lactamases (ESBLs) in Urinary Isolates of Klebsiella Pneumoniae
Abstract Background and Objective: Klebsiella pneumoniae is an opportunistic nosocomial pathogen causing a variety of infections including urinary tract infections, pneumonia, septicemia, wound infections and infections in the intensive care units. Since the ESBL producing Klebsiella pneumoniae strains are increasingly causing urinary tract infections, we aim to assess antibiotic resistance pat...
متن کاملMultiple antibiotic-resistance mechanisms including a novel combination of extended-spectrum beta-lactamases in a Klebsiella pneumoniae clinical strain isolated in Argentina.
Klebsiella pneumoniae M1803, isolated from a paediatric patient with chronic urinary infection, presented nine antimicrobial resistance mechanisms harboured on two conjugative megaplasmids, in addition to the chromosomally mediated SHV-1 beta-lactamase. These nine antimicrobial resistance mechanisms comprised two extended-spectrum beta-lactamases (ESBLs) (PER-2 and CTX-M-2), TEM-1-like, OXA-9-l...
متن کامل